Slightly viscous liquid. Faintly bitter taste followed by a faint sensation of warmth.
298
7.52
Other
Room Temperature
C10 H14 N2O
<10 ppm
98%
Pharmaceutical Intermediates
2.2.32
miscible with water,96% ethanol,chloroform and Ether in all proportions
N,N-Diethyl-3-pyridinecarboxamide
29033919
Nikethamide
Nikethamide is a stimulant which mainly affects the respiratory cycle. Widely known by its former trade name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion.
C10 H14 N2O
Liquid
Medicine Grade
Other
Nikethamide BP Trade Information
india
Cash Advance (CA) Letter of Credit (L/C) Letter of Credit at Sight (Sight L/C) Cash Against Delivery (CAD) Telegraphic Transfer (T/T) Cash in Advance (CID)
1000 Kilograms Per Day
7 Days
Free samples are available
DRUM
Western Europe North America Eastern Europe Middle East Africa South America Australia Asia Central America
ISO,GMP
Product Description
Nikethamide is an antifungal agent used for long periods at high doses, especially in immunosuppressed patients. It is a racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-ketoconazole with the chiral centers on the acetal ring. It is used to treat certain serious fungal infections in the body. It belongs to the class of drugs called azole antifungals. It works by stopping the growth of the fungus. This drug is used to treat fungal infections on the skin and nails due to the risk of serious side effects and drug interactions.
Nikethamide Properties:
CAS Registry No.: 59-26-7
CAS Name: N,N-Diethyl-3-pyridinecarboxamide
Form: Liquid that is slightly viscous. An initial taste of bitterness followed by a feeling of warmth.
Molecular Formula: C10H14N2O
Molecular Weight: 178.23
How to use
Nikethamide acts similarly as doxapram hydrochloride and it was formerly given subcutaneously, intravenously, intramuscularly or orally to treat the overdose because of nervous system depressants, like morphine, barbiturates and anticholinesterases, and in patients who have chronic respiratory acidosis.
Side effects
Nikethamide also causes nausea, muscle twitching, and vomiting, in addition to generalized restlessness.