Croscarmellose Sodium

350.0 INR/Kilograms

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Product Details:

Melting Point 1710 C
Molecular Weight 240.21 g/mol Kilograms (kg)
Heavy Metal (%) NA
Shelf Life 5 Years
Boiling point 2230
Solubility Practically insoluble in acetone and anhydrous ethanol
Particle Size 25 to 55 m
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Croscarmellose Sodium Price And Quantity

Price Range 200.00 - 300.00 INR/Kilograms
Price 350.0 INR/Kilograms
Minimum Order Quantity 25 Kilograms

Croscarmellose Sodium Product Specifications

Storage Room Temperature
HS Code 39123100
Purity(%) 98%
Medicine Name Croscarmellose Sodium
CAS No 74811-65-7
Type Pharmaceutical Intermediates
Molecular Formula C8H16O8
Structural Formula C28H30Na8O27
Smell No Smell
Taste Odorless
EINECS No 1272/2008
Ph Level 5.7
Solubility Practically insoluble in acetone and anhydrous ethanol
Particle Size 25 to 55 m
Shelf Life 5 Years
Boiling point 2230
Physical Form Powder
Loss on Drying 2.41= Not more than 0.5z
Usage Sodium carboxymethylcellulose crosslinked (Croscarmellose Sodium) has several important uses in the pharmaceutical, food, and other industries. Here are its main applications: 1. Pharmaceutical Uses: Disintegrant in Tablets and Capsules: Its primary role in medicines is to help tablets or capsules break down or "disintegrate" once ingested, ensuring that the active ingredients are released efficiently in the digestive tract. Controlled-Release Formulations: It can also be used in extended-release formulations, where it controls the release of the active drug over time. Binders and Stabilizers: In some formulations, it helps bind the components of the pill and stabilize the drug's effectiveness. 2. Food Industry: Food Additive: It is used as a thickening agent or stabilizer in some processed foods, such as ice cream, salad dressings, and soups. Texture Modifications: It helps improve the texture and consistency of certain food products. 3. Cosmetics and Personal Care: Stabilizer in Creams and Lotions: It is used to stabilize emulsions in products like lotions, creams, and shampoos, ensuring smooth consistency. Gelling Agent: Used in the formulation of gels and other cosmetic products to improve texture. 4. Other Uses: Industrial Applications: In some cases, it is used in the production of paper and textiles as a thickening agent. Its ability to rapidly absorb water and form a gel makes it versatile across different sectors!
Chemical Name sodium carboxymethylcellulose crosslinked
Grade Medicine Grade
Heavy Metal (%) NA
Molecular Weight 240.21 g/mol Kilograms (kg)
Appearance White Free Flowing Powder
Melting Point 1710 C

Croscarmellose Sodium Trade Information

FOB Port India
Payment Terms Cash Advance (CA) Cash in Advance (CID) Days after Acceptance (DA) Delivery Point (DP) Letter of Credit at Sight (Sight L/C) Letter of Credit (L/C)
Supply Ability 100 Kilograms Per Day
Delivery Time 7 Days
Sample Available Yes
Sample Policy Free samples are available
Packaging Details Drum / Bag Packing
Main Export Market(s) Asia Australia Central America North America South America Eastern Europe Western Europe Middle East Africa
Main Domestic Market All India
Certifications GMP/ ISO

Product Description

Croscarmellose sodium is a sodium salt of a cross-linked carboxymethylcellulose polymer. It is a commonly used pharmaceutical excipient that is used as a disintegrant in tablet formulations. It works by absorbing water and swelling rapidly, creating channels in the tablet that allow water to penetrate and dissolve the drug more easily. This helps to break down the tablet into smaller particles that can be easily dissolved in the gastrointestinal tract.

Croscarmellose sodium can improve the dissolution and bioavailability of drugs, enhance the stability of suspensions and emulsions, and control the rate of drug release in controlled-release tablets. It is also easy to use and cost-effective.

Croscarmellose sodium is generally considered safe for use in pharmaceuticals. It has been used for many years and is approved by regulatory agencies such as the FDA. While it is primarily used in pharmaceuticals, it can also be used in other industries such as food and cosmetics as a thickener, stabilizer, and emulsifier.

Croscarmellose Sodium Properties:

CAS Number: 74811-65-7
Molecular Formula: C₈H₁₆O₈
Molecular Weight: 240.21 g/mol
Melting Point: 171 Degree Centigrade
Boiling Point: 223 Degree Centigrade
Solubility: Practically insoluble in anhydrous ethanol, toluene and acetone
Synonyms: Carboxymethylcellulose Cellulose, carboxymethyl ether

Croscarmellose Sodium Applications:

1. Disintegrant: Croscarmellose sodium is primarily used as a disintegrant in tablet formulations. It helps to break down the tablet into smaller particles that can be easily dissolved in the gastrointestinal tract.

2. Binder: It is also used as a binder in the formulation of tablets. It helps to hold the ingredients together and prevent the tablet from falling apart.

3. Stabilizer: Croscarmellose sodium can also be used as a stabilizer in the formulation of suspensions and emulsions. It helps to prevent the separation of the different phases of the formulation.

4. Controlled release: Croscarmellose sodium can be used in the formulation of controlled-release tablets. It can control the rate of drug release by creating a barrier around the tablet and preventing the drug from being released too quickly.

5. Solubility enhancement: Croscarmellose sodium can enhance the solubility of poorly soluble drugs. It can do this by creating channels in the tablet that allow water to penetrate and dissolve the drug more easily.

How does it work:

CMC or carboxymethylcellulose (CMC) is a major ingredient in pharmaceuticals, and is widely used as a disintegrant in oral pharmaceutical formulations for capsules, tablets, and granules.

Side effects:

You cannot experience any "side effects" from croscarmellose sodium unless your body directly reacts to it. It has only been approved for use in small amounts by the Food and Drug Administration. It is not very likely to cause allergies. It can also cause adverse side effects in some, such as dyspepsia, hepatotoxicity, pancreatitis, interstitial nephritis, fever, headache, rash, nausea, vomiting, pneumonitis, pericarditis and so on.

Frequently Asked Questions:

1. What is croscarmellose sodium?

Ans: It is a sodium salt of a cross-linked carboxymethylcellulose polymer. It is a commonly used pharmaceutical excipient that is used as a disintegrant in tablet formulations.

2. How does croscarmellose sodium work?

Ans: It works by absorbing water and swelling rapidly, creating channels in the tablet that allow water to penetrate and dissolve the drug more easily. This helps to break down the tablet into smaller particles that can be easily dissolved in the gastrointestinal tract.

3. What are the benefits of using croscarmellose sodium in tablet formulations?

Ans: It can improve the dissolution and bioavailability of drugs, enhance the stability of suspensions and emulsions, and control the rate of drug release in controlled-release tablets. It is also easy to use and cost-effective.

4. Is croscarmellose sodium safe?

Ans: Yes, it is generally considered safe for use in pharmaceuticals. It has been used for many years and is approved by regulatory agencies such as the FDA.

5. Can croscarmellose sodium be used in other applications besides pharmaceuticals?

Ans: While croscarmellose sodium is primarily used in pharmaceuticals, it can also be used in other industries such as food and cosmetics as a thickener, stabilizer, and emulsifier. However, it is important to note that the grade of croscarmellose sodium used in pharmaceuticals may differ from the grade used in other industries, and care should be taken to ensure that the appropriate grade is used for the intended application.

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